|
KMID : 0370019980120000073
|
|
Chung-Ang Journal of Pharmacal Sciences
1998 Volume.12 No. 0 p.73 ~ p.79
|
|
|
BRM Response of Pedunculagin (purified tannin)
|
|
|
|
|
Abstract
|
|
|
|
Pedunculagin, an ellagitannin from Alrus hirsuta var. microphylla, Betulaceae was evaluated on the antitumor activity. To investigate cytotoxicity of pedunculagin on tumor cells, the effect of the substance on three cell lines(P815, Yac-1, B16-F20) was examined. And the result was somewhat different among three cell lines. The growth-rate of P815 was not cut down significantly, but in contrast, the inhibitory activities on Yac-1 and B16-F10 were effective. ED_50s of pedunculagin against P815, Yac-1 and B16-F10 were 12.16, 1.89, 3.30㎍/㎖ respectively.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|